Surrozen, Inc.
NASDAQ•SRZN
CEO: Mr. Craig C. Parker M.B.A.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2021-01-11
Surrozen, Inc., a clinical stage biotechnology company, discovers and develops drug candidates to selectively modulate the Wnt pathway for tissue repair. The company is developing antibody-based therapeutics which targets various disease areas, including diseases of the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system. Its products in pipeline include SZN-043, a hepatocyte-specific R-spondin mimetic bispecific fusion protein, which is in Phase 1b clinical trial for the treatment of severe liver diseases, including alcohol-associated hepatitis. The company develops SZN-413, a Fzd4 targeted bi-specific antibody for the treatment of retinal vascular associated diseases. Surrozen, Inc. has collaboration and license agreement with Boehringer Ingelheim International GmbH to research, develop, and commercialize Fzd4 bi-specific antibodies. Surrozen, Inc. is based in South San Francisco, California.
Contact Information
171 Oyster Point Boulevard, Suite 400, South San Francisco, CA, 94080, United States
650-489-9000
Market Cap
$197.18M
P/E (TTM)
-0.8
23
Dividend Yield
--
52W High
$35.00
52W Low
$7.37
52W Range
Rank43Top 50.7%
3.8
F-Score
Modified Piotroski Analysis
Based on 6-year fundamentals
Weak • 3.8 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2020-2025
Financial Dashboard
Q1 2026 Data
Revenue
$5.00M+0.00%
4-Quarter Trend
EPS
-$11.65+0.00%
4-Quarter Trend
FCF
-$12.62M+0.00%
4-Quarter Trend
2025 Annual Earnings Highlights
Key Highlights
Net Loss Widens Significantly Net loss reached $(242.0M) USD in 2025, up from $(63.6M) USD in 2024, driven by R&D expansion.
Revenue Drops Post-Milestone Total revenue fell 67% to $3.5M USD in 2025 after 2024 recognized $10.0M collaboration milestone.
R&D Spending Increased 39% Research and development expenses rose $8.2M USD to $29.4M USD, supporting ophthalmology programs advancement.
Strong Financing Bolsters Cash Net cash increased $54.7M USD in 2025, primarily from $74.7M USD net proceeds from the 2025 PIPE financing.
Risk Factors
Continued Operating Losses Expected Company has history of losses; expects continued significant losses, requiring substantial additional capital for development.
Clinical Development Uncertainty Clinical trials face delays from enrollment difficulties, regulatory hurdles, and potential negative safety or efficacy results.
Manufacturing and Supply Reliance Reliance on third-party CMOs for complex antibody manufacturing poses risks of delays or supply interruptions.
Intellectual Property Challenges Patent portfolio faces challenges, including ongoing review of a key patent challenged by Merck in February 2026.
Outlook
Advance Key Ophthalmology Candidates Strategy focuses on advancing SZN-8141 and SZN-8143 through clinical development for retinal diseases.
SZN-8141 IND Submission Planned Anticipate submitting IND for SZN-8141 in the second half of 2026 to initiate human clinical trials.
Platform Expansion Strategy Intends to exploit Wnt platform to discover and develop portfolio candidates for various tissue repair indications.
Future Capital Needs Anticipated Expect to raise additional capital through equity or debt financing to fund long-term operations and growth plans.
Peer Comparison
Revenue (TTM)
$123.87M
$22.33M
$15.04M
Gross Margin (Latest Quarter)
100.0%
99.4%
98.7%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| GLSI | $383.08M | -19.4 | -1042.8% | 0.0% |
| IRD | $346.74M | -34.6 | 6068.8% | 38.8% |
| NAUT | $322.78M | -5.6 | -35.0% | 16.2% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
72.0%
Strong Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Deep Research
Next earnings:Aug 14, 2026
EPS:-$1.29
|Revenue:$467.25K
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement | LTM |
|---|
No Data