Arcellx, Inc.
NASDAQ•ACLX
CEO: Mr. Rami Elghandour
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2022-02-04
Arcellx, Inc., together with its subsidiary, engages in the development of various immunotherapies for patients with cancer and other incurable diseases in the United States. The company's lead ddCAR product candidate is anitocabtagene autoleucel, which is in phase 2 clinical trial for the treatment of patients with relapsed or refractory multiple myeloma (rrMM). It also develops ACLX-001, a product candidate in Phase 1 clinical trials targeting BCMA to treat rrMM; and ACLX-002, which is in Phase 1 clinical trials that targets CD123 for treating relapsed or refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). In addition, the company's preclinical product includes ACLX-003 for the treatment of AML and MDS. Further, it focuses on the development of product candidates for solid tumor programs. It has a strategic alliance with Kite Pharma, Inc. to co-develop and co-commercialize anitocabtagene autoleucel. The company was formerly known as Encarta Therapeutics, Inc. and changed its name to Arcellx, Inc. in January 2016. Arcellx, Inc. was incorporated in 2014 and is headquartered in Redwood City, California.
Contact Information
Market Cap
$6.70B
P/E (TTM)
-28.2
17.8
Dividend Yield
--
52W High
$114.80
52W Low
$47.86
52W Range
Rank47Top 61.9%
3.4
F-Score
Modified Piotroski Analysis
Based on 7-year fundamentals
Weak • 3.4 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2019-2025
Financial Dashboard
Q4 2025 Data
Revenue
$1.65M+0.00%
4-Quarter Trend
EPS
-$1.01+0.00%
4-Quarter Trend
FCF
-$58.94M+0.00%
4-Quarter Trend
2025 Annual Earnings Highlights
Key Highlights
Anito-cel BLA Accepted FDA accepted BLA for anito-cel treatment of rrMM; anticipated Prescription Drug User Fee Act date is December 23, 2026.
Pivotal Trial Shows Strong Response iMMagine-1 trial reported 96% overall response rate and 74% stringent/complete response rate in refractory patients.
Gilead Acquisition Terms Gilead merger offer set at $115.00 per share plus one CVR; expected closing anticipated in the second quarter of 2026.
Extended Cash Runway Cash and marketable securities totaled $520.1 M as of year-end 2025, funding operations projected into 2028.
Risk Factors
Collaboration Revenue Decline Collaboration revenue dropped 79% to $22.3 M in 2025, primarily due to completion of dosing/manufacturing milestones in iMMagine-1.
Widening Net Loss Net loss increased 113% to $(228.9 M) in 2025, driven by 33% rise in G&A expenses to $117.8 M.
Merger Termination Cost Merger closing is subject to conditions; termination under specific circumstances requires paying Gilead a $260.0 M termination fee.
Novel Platform Execution ddCAR and ARC-SparX platforms are novel and unproven, complicating development timelines and regulatory approval success.
Outlook
Phase 3 Trial Enrollment Kite is running global Phase 3 iMMagine-3 trial for anito-cel; expects trial enrollment completion by the middle of 2026.
Pipeline Diversification Advancing ACLX-002/004 for AML/MDS and evaluating anito-cel in non-oncology indications, starting with generalized Myasthenia Gravis.
Technology Platform Expansion Plan to leverage proprietary D-Domain technology to expand pipeline into solid tumors and autoimmune disease indications.
Commercial Infrastructure Build Establishing commercial organization and distribution capabilities now, anticipating substantial future investment prior to product approval.
Peer Comparison
Revenue (TTM)
$1.73B
$1.48B
$1.09B
Gross Margin (Latest Quarter)
2763.6%
111.8%
100.0%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| PCVX | $8.54B | -10.5 | -25.9% | 7.5% |
| ARWR | $8.50B | 42.0 | 36.1% | 19.5% |
| KYMR | $6.94B | -23.0 | -29.1% | 4.7% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
-41.2%
Growth Under Pressure
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Deep Research
Next earnings:Mar 17, 2026
EPS:-
|Revenue:-
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement | LTM |
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No Data