
Arcellx, Inc.
NASDAQ•ACLX
CEO: Mr. Rami Elghandour
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2022-02-04
Arcellx, Inc., together with its subsidiary, engages in the development of various immunotherapies for patients with cancer and other incurable diseases in the United States. The company's lead ddCAR product candidate is anitocabtagene autoleucel, which is in phase 2 clinical trial for the treatment of patients with relapsed or refractory multiple myeloma (rrMM). It also develops ACLX-001, a product candidate in Phase 1 clinical trials targeting BCMA to treat rrMM; and ACLX-002, which is in Phase 1 clinical trials that targets CD123 for treating relapsed or refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). In addition, the company's preclinical product includes ACLX-003 for the treatment of AML and MDS. Further, it focuses on the development of product candidates for solid tumor programs. It has a strategic alliance with Kite Pharma, Inc. to co-develop and co-commercialize anitocabtagene autoleucel. The company was formerly known as Encarta Therapeutics, Inc. and changed its name to Arcellx, Inc. in January 2016. Arcellx, Inc. was incorporated in 2014 and is headquartered in Redwood City, California.
Contact Information
Market Cap
$3.99B
P/E (TTM)
-21.5
42.6
Dividend Yield
--
52W High
$94.07
52W Low
$47.86
52W Range
Rank56Top 70.4%
2.9
F-Score
Modified Piotroski Analysis
Based on 7-year fundamentals
Weak • 2.9 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2018-2024
Financial Dashboard
Q3 2025 Data
Revenue
$4.95M-80.99%
4-Quarter Trend
EPS
-$0.99+106.25%
4-Quarter Trend
FCF
-$49.50M-274.13%
4-Quarter Trend
2025 Q3 Earnings Highlights
Key Highlights
Collaboration Revenue Decreases Sharply Nine months revenue $20.6M, down $72.0M, driven by completion of dosing and manufacturing for anito-cel iMMagine-1 trial.
Research Development Spending Rises Nine months R&D expenses totaled $123.5M, up $11.1M, primarily due to higher internal personnel costs incurred during the period.
Cash Runway Extended Through 2028 Total cash and marketable securities $576.0M as of September 30, 2025, sufficient to fund operations into 2028.
Net Loss Significantly Widens Nine months net loss reached $(170.8M), a substantial increase from $(60.3M) loss reported in the prior year period.
Risk Factors
Late-Stage Candidate Success Uncertain Only one product candidate in late-stage development; novel platform success and regulatory approval remain highly uncertain.
Substantial Additional Funding Needed Limited operating history and incurred significant losses; substantial additional funding required to advance pipeline candidates.
Reliance on Third-Party Manufacturing Manufacturing genetically engineered products is complex; reliance on third parties exposes company to supply constraints or quality issues.
Potential Future Clinical Holds FDA previously issued partial clinical hold on anito-cel; future holds could cause material delays and harm prospects.
Outlook
Advance Clinical Pipeline Programs Plans include advancing anito-cel into earlier lines of therapy and continuing Phase 1 trials for ARC-SparX candidates.
Increase Commercial Readiness Spending Expect general and administrative expenses to increase as headcount expands preparing for potential commercial launch of anito-cel.
Seek Future Strategic Collaborations Expect to seek future collaborations for development or commercialization, dependent on favorable terms and resource allocation.
Maintain Intellectual Property Portfolio Continue to develop proprietary platforms and maintain, expand, and protect intellectual property portfolio for competitive advantage.
Peer Comparison
Revenue (TTM)
PTCT$1.78B
ALKS$1.52B
ARWR$596.57M
Gross Margin (Latest Quarter)
PTCT92.5%
ALKS86.9%
NAMS81.6%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| ARWR | $9.53B | -64.6 | -41.2% | 51.7% |
| KYMR | $6.47B | -26.6 | -33.4% | 7.6% |
| PTCT | $5.95B | 7.7 | -182.7% | 15.5% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
-31.3%
Growth Under Pressure
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Research & Insights
Next earnings:Feb 26, 2026
EPS:-$1.01
|Revenue:-
Reports
All Years
Form 10-Q - Q3 2025
Period End: Sep 30, 2025|Filed: Nov 5, 2025|Revenue: $4.95M-81.0%|EPS: $-0.99+106.3%MeetForm 10-Q - Q2 2025
Period End: Jun 30, 2025|Filed: Aug 7, 2025|Revenue: $7.55M-72.4%|EPS: $-0.94+84.3%MeetForm 10-Q - Q1 2025
Period End: Mar 31, 2025|Filed: May 8, 2025|Revenue: $8.13M-79.3%|EPS: $-1.13+707.1%MissForm 10-K - FY 2024
Period End: Dec 31, 2024|Filed: Feb 27, 2025|Revenue: $107.94M-2.2%|EPS: $-2.00-36.1%MissForm 10-Q - Q3 2024
Period End: Sep 30, 2024|Filed: Nov 7, 2024|Revenue: $26.03M+74.0%|EPS: $-0.48-40.7%MissForm 10-Q - Q2 2024
Period End: Jun 30, 2024|Filed: Aug 8, 2024|Revenue: $27.38M+91.5%|EPS: $-0.51+2.0%BeatForm 10-Q - Q1 2024
Period End: Mar 31, 2024|Filed: May 9, 2024|Revenue: $39.26M+119.2%|EPS: $-0.14-75.9%BeatForm 10-K - FY 2023
Period End: Dec 31, 2023|Filed: Feb 28, 2024|Revenue: $110.32M+0.0%|EPS: $-1.47+65.7%Miss