logo
logo
MESO stock ticker logo

Mesoblast Limited

NASDAQ•MESO
CEO: Dr. Silviu Itescu FACP, FACRA, FRACP, MBBS (Hons)
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2010-01-20
Mesoblast Limited engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. Its proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. The company offers Remestemcel-L that is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease and biologic refractory inflammatory bowel disease, as well as Crohn's disease; and Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease. It is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM for the treatment or prevention of chronic heart failure and MPC-25-IC for the treatment or prevention of acute myocardial infarction; JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa and for the treatment of neonatal hypoxic ischemic encephalopathy; and Grünenthal to develops and commercializes cell therapy for the treatment of chronic low back pain. The company was incorporated in 2004 and is headquartered in Melbourne, Australia.
Contact Information
55 Collins Street, Level 38, Melbourne, VIC, 3000, Australia
61-3-9639-6036
www.mesoblast.com
Market Cap
$1.94B
P/E (TTM)
-18.6
17.5
Dividend Yield
--
52W High
$21.50
52W Low
$9.61
52W Range
46%
Rank60Top 89.2%
2.1
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 2.1 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$7.02M+458.55%
4-Quarter Trend

EPS

-$0.21-16.00%
4-Quarter Trend

FCF

-$14.94M+17268.02%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Total Revenue Jumps 191% Total revenues reached $17.2M in FY2025, up 191% from $5.9M in FY2024, driven by Ryoncil launch activities.
Ryoncil Commercial Launch Success Recognized $11.3M in net product sales from Ryoncil launch starting March 2025; 25 transplant centers onboarded.
Strengthened Cash Position Cash reserves increased to $161.6M by June 30, 2025, supported by $161.0M capital raise completed in January 2025.
R&D Expenses Decrease R&D expenses fell 12% to $34.8M in FY2025, primarily due to reversal of pre-launch inventory provision upon approval.

Risk Factors

Continued Operating Losses Expected Incurred accumulated losses of $1.01B since inception; anticipates substantial operating losses for the foreseeable future.
Commercialization Success Dependence Business success substantially dependent on Ryoncil sales until next product candidate achieves regulatory approval and market acceptance.
Manufacturing Supply Chain Reliance Relies on contract manufacturer Lonza for commercial scale production; disruptions could severely affect operations and costs.
Regulatory Hurdles Remain High Novel cell therapy development faces high failure rates, complex regulatory requirements, and potential clinical delays impacting timelines.

Outlook

Advance Ryoncil Label Expansion Plans pivotal controlled study for Ryoncil in high-risk adult SR-aGVHD patients, targeting label extension opportunities.
Finalizing Debt Refinancing Plans In advanced stages of finalizing plans to refinance existing debt arrangements within the next twelve months to address repayments.
Progress Revascor Development Seeking accelerated approval pathway for Revascor (HFrEF); alignment achieved with FDA on CMC and trial design components.
Focus on Core Strategic Imperatives Strategy centers on optimizing disruptive technology platform, prioritizing late-stage portfolio, and strengthening intellectual property estate.

Peer Comparison

Revenue (TTM)

SRPT stock ticker logoSRPT
$2.20B
+15.6%
GLPG stock ticker logoGLPG
$1.26B
+303.5%
TVTX stock ticker logoTVTX
$490.73M
+110.5%

Gross Margin (Latest Quarter)

LQDA stock ticker logoLQDA
101.7%
+29.3pp
NUVB stock ticker logoNUVB
99.0%
+182.9pp
IBRX stock ticker logoIBRX
88.9%
-12.9pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
IBRX$8.04B-22.064.3%175.0%
COGT$5.73B-7.3-100.2%27.0%
CELC$5.13B-30.5-179.0%67.3%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
64.5%
Strong Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention

Deep Research

Next earnings:Sep 2, 2026
|
EPS:-$0.06
|
Revenue:$75.40M
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement
LTM
No Data