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Capricor Therapeutics, Inc.

NASDAQ•CAPR
CEO: Dr. Frank Isaac Litvack FACC, M.D.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2007-02-13
Capricor Therapeutics, Inc., a clinical-stage biotechnology company, focuses on the development of transformative cell and exosome-based therapeutics for the treatment of duchenne muscular dystrophy (DMD) and other diseases with unmet medical needs. The company's lead candidate, CAP-1002, an allogeneic cardiac-derived cell therapy, which has completed phase 3 clinical trial for the treatment of patients with late-stage Duchenne muscular dystrophy (DMD). It also focused on developing StealthX, an engineered exosome-based vaccine candidate, under phase 1 clinical study for a range of therapeutic applications, including targeted RNA, protein, and small molecule therapeutics to treat or prevent a variety of diseases. In addition, the company develops CAP-2003, under pre-clinical development for the treatment of trauma related injuries and conditions. It has collaboration and distribution agreement with Nippon Shinyaku Co. Ltd., collaboration agreement with National Institute of Allergy and Infectious Diseases, license agreements with the Johns Hopkins University and Cedars-Sinai Medical Center, as well as cell line license agreement with Life Technologies Corporation. The company was founded in 2005 and is headquartered in San Diego, California.
Contact Information
10865 Road to the Cure, Suite 150, San Diego, CA, 92121, United States
858-727-1755
www.capricor.com
Market Cap
$1.54B
P/E (TTM)
-15.6
18.1
Dividend Yield
--
52W High
$40.37
52W Low
$4.30
52W Range
81%
Rank48Top 64.4%
3.3
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 3.3 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$0.00+0.00%
4-Quarter Trend

EPS

-$0.62+0.00%
4-Quarter Trend

FCF

-$28.69M+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Strong Cash Position Achieved Cash and securities total $318.1M, up from $151.5M due to $237.0M net proceeds from December 2025 stock offering.
Deramiocel BLA Resubmission Complete BLA resubmission accepted; FDA assigned new PDUFA target action date of August 22, 2026, for DMD treatment.
HOPE-3 Trial Positive Results HOPE-3 showed 54% slowing in PUL v2.0 score and 91% slowing in LVEF percentage change versus placebo.
Operating Expenses Increased Substantially Total R&D expenses rose 69% to $84.5M in 2025, driven by Deramiocel clinical costs and headcount expansion.

Risk Factors

Regulatory Approval Uncertainty Remains Success hinges on regulatory approval; previously received Complete Response Letter requesting additional clinical data.
Need Additional Funding Capital Expect substantial future losses; inability to raise capital forces delay, reduction, or elimination of product development programs.
Manufacturing Complex Supply Chains Deramiocel production relies on complex supply chains and third-party vendors; disruptions risk delays or product failure.
Competition Threatens Market Success Approved products face intense competition from existing exon-skipping and gene therapies targeting Duchenne muscular dystrophy.

Outlook

Advance Deramiocel US Commercialization Preparing for potential US commercialization of Deramiocel, including expanding manufacturing capabilities and securing supply.
Advance Exosome Platform Programs Strategy focuses on advancing StealthX vaccine through Phase 1 study and exploring therapeutic applications via partnerships.
Finalize European Distribution Agreement Working to finalize definitive agreement with Nippon Shinyaku for Deramiocel distribution in the European region by April 2026.
Seek Strategic Partnership Funding Actively seeking strategic collaborations to accelerate development timelines and expand pipeline beyond current core focus areas.

Peer Comparison

Revenue (TTM)

VNDA stock ticker logoVNDA
$216.11M
+8.7%
ARCT stock ticker logoARCT
$74.12M
-46.4%
SCPH stock ticker logoSCPH
$49.97M
+107.8%

Gross Margin (Latest Quarter)

EDIT stock ticker logoEDIT
100.0%
+2621.3pp
ACIU stock ticker logoACIU
100.0%
+0.0pp
VNDA stock ticker logoVNDA
93.3%
+0.1pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
CAPR$1.54B-15.6-67.5%5.9%
ALLO$519.44M-2.5-57.1%20.0%
TRDA$516.84M-3.9-39.8%13.5%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
N/M
Revenue Volatile
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention

Deep Research

Next earnings:May 7, 2026
|
EPS:-$0.52
|
Revenue:-
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement
LTM
No Data