Immatics N.V.
NASDAQ•IMTX
CEO: Dr. Harpreet Singh Ph.D.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2018-12-12
Immatics N.V., a clinical-stage biopharmaceutical company, focuses on the research and development of potential T cell redirecting immunotherapies for the treatment of cancer in the United States. The company is developing targeted immunotherapies with a focus on treating solid tumors through two distinct treatment modalities, such as TCR-engineered autologous or allogeneic adoptive cell therapies (ACT) and antibody-like TCR Bispecifics. Its products pipeline includes IMA203 that targets solid tumors, which is in Phase 1b clinical trial; IMA203CD8, a cell therapy product that is in Phase 1b clinical trial; IMA204 that targets tumor stroma, which is in preclinical stage; and IMA30x, an allogenic cellular therapy product candidate, which is in preclinical stage. The company also develops TCR Bispecifics products, including IMA401 and IMA402, which is in Phase 1a clinical trial. The company has a strategic collaboration agreement with MD Anderson Cancer Center to develop multiple T cell and TCR-based adoptive cellular therapies; Celgene Corporation to develop novel adoptive cell therapies targeting multiple cancers; and Genmab A/S to develop T cell engaging bispecific immunotherapies targeting multiple cancer indications. Immatics N.V. is headquartered in Tübingen, Germany.
Contact Information
Market Cap
$1.24B
P/E (TTM)
-5.4
17.9
Dividend Yield
--
52W High
$12.41
52W Low
$3.30
52W Range
Rank61Top 91.5%
2.0
F-Score
Modified Piotroski Analysis
Based on 7-year fundamentals
Weak • 2 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2019-2025
Financial Dashboard
Q4 2025 Data
Revenue
$22.79M+0.00%
4-Quarter Trend
EPS
-$0.33+0.00%
4-Quarter Trend
FCF
-$68.21M+0.00%
4-Quarter Trend
2025 Annual Earnings Highlights
Key Highlights
anzu-cel Advanced Melanoma Data Phase 1b cORR 56% (18/32) in advanced melanoma; median OS 15.9 months; BLA submission targeted 1H 2027.
GEN2 Cell Therapy Activity IMA203CD8 showed 36% cORR (23/64) across solid tumors; deep responses up to 3+ years observed in trials.
Strong Cash Position Maintained Cash and equivalents €345.9M as of Dec 31, 2025; funded operations via €107.2M public offering proceeds in 2025.
Risk Factors
History of Operating Losses Operating result €182.0M loss in 2025; expect continued significant losses until commercial revenue generation begins.
Clinical Trial Execution Risks Trials face delays from recruitment challenges, regulatory hurdles, and complex manufacturing processes for novel therapies.
Capital Needs and Dilution Requires substantial future capital; equity raises risk shareholder dilution or debt financing imposes restrictive covenants.
Outlook
anzu-cel Regulatory Path Targeting BLA submission for anzu-cel in 1H 2027, aiming for U.S. market launch in 2H 2027, pending approval.
IMA203CD8 Development Advancement Complete dose escalation and determine RP2D for IMA203CD8 in 2026; focus on tumor-agnostic positioning in gynecologic cancers.
IMA402 Bispecific Milestones RP2D determination and Phase 1 data update for IMA402 planned for 2H 2026; initiate IMA402/IMA401 combo in 2026.
Peer Comparison
Revenue (TTM)
$407.32M
$172.35M
$90.49M
Gross Margin (Latest Quarter)
102.3%
100.0%
99.3%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| TERN | $4.19B | -45.2 | -30.0% | 0.3% |
| WVE | $2.45B | -11.5 | -85.0% | 2.8% |
| SYRE | $2.41B | -88.9 | -29.4% | 0.0% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
5.2%
Steady Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Deep Research
Next earnings:Mar 26, 2026
EPS:-$0.48
|Revenue:-
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement | LTM |
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No Data