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Adaptive Biotechnologies Corporation

NASDAQ•ADPT
CEO: Mr. Chad M. Robins M.B.A.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2019-06-27
Adaptive Biotechnologies Corporation, a commercial-stage company, develops an immune medicine platform for the diagnosis and treatment of various diseases. The company offers immunosequencing platform which combines a suite of proprietary chemistry, computational biology, and machine learning to generate clinical immunomics data to decode the adaptive immune system. It also provides clonoSEQ diagnostic test which detects and monitors the remaining number of cancer cells that are present in a patient's body during and after treatment, known as Minimal Residual Disease (MRD). The company offers products and services for life sciences research, clinical diagnostics, and drug discovery applications. Adaptive Biotechnologies Corporation has strategic collaborations with Genentech, Inc. for the development, manufacture, and commercialization of neoantigen directed T cell therapies for the treatment of a range of cancers; and Microsoft Corporation to develop diagnostic tests for the early detection of various diseases from a single blood test. The company was formerly known as Adaptive TCR Corporation and changed its name to Adaptive Biotechnologies Corporation in December 2011. Adaptive Biotechnologies Corporation was incorporated in 2009 and is headquartered in Seattle, Washington.
Contact Information
1165 Eastlake Avenue East, Seattle, WA, 98109, United States
206-659-0067
www.adaptivebiotech.com
Market Cap
$2.48B
P/E (TTM)
-41.5
19.5
Dividend Yield
--
52W High
$20.76
52W Low
$6.26
52W Range
68%
Rank57Top 83.3%
2.4
F-Score
Modified Piotroski Analysis
Based on 8-year fundamentals
Weak • 2.4 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2018-2025

Financial Dashboard

Q4 2025 Data

Revenue

$71.68M+0.00%
4-Quarter Trend

EPS

-$0.09+0.00%
4-Quarter Trend

FCF

$1.42M+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Total Revenue Growth 55% Total revenue reached $277.0M USD in 2025, marking a 55% increase from $179.0M USD in 2024.
Net Loss Significantly Narrowed Net loss narrowed to $(59.5M) USD in 2025, a reduction of $100.1M USD compared to the prior year loss.
MRD Revenue Increased 46% MRD revenue grew 46% to $212.3M USD in 2025, driven by 39% growth in clonoSEQ test volume delivered.
Cash Burn Reduced 52% Net cash used in operating activities decreased 52% to $46.0M USD in 2025 from $95.2M USD in 2024.

Risk Factors

Payor Coverage Uncertainty Diagnostic revenue depends on achieving broad payor coverage; policies declining coverage risk demand and limit commercial success.
Supplier Reliance Risks Reliance on limited suppliers for sequencers and reagents could cause processing delays, increase costs, and disrupt operations.
Intellectual Property Enforcement Patent portfolio strength faces challenges; litigation costs and potential invalidation could adversely affect competitive position.
Continued Operating Losses Expect continued significant expenses and operating losses while investing heavily in platform development and future expansion.

Outlook

Expand clonoSEQ Adoption Strategy focuses on increasing clinical testing in blood and expanding clonoSEQ utility across all lymphoid malignancies.
IM Platform Monetization Pursuing target discovery and data licensing opportunities leveraging proprietary TCR-antigen mapping datasets with partners.
Improve Cost Per Sample Expect cost per sample to decrease long-term due to improved utilization, automation, and value engineering initiatives.
International Market Progress Anticipate making progress in 2026 by obtaining necessary regulatory approval to enable clonoSEQ testing in Canada.

Peer Comparison

Revenue (TTM)

GLPG stock ticker logoGLPG
$1.26B
+303.5%
LEGN stock ticker logoLEGN
$908.96M
+74.7%
CPRX stock ticker logoCPRX
$588.99M
+19.8%

Gross Margin (Latest Quarter)

AGIO stock ticker logoAGIO
96.9%
-4.3pp
BEAM stock ticker logoBEAM
95.0%
-471.3pp
TARS stock ticker logoTARS
92.8%
-14.0pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
IBRX$10.28B-29.464.3%175.0%
CDTX$5.61B-18.6-60.1%0.4%
SRRK$4.44B-14.0-122.0%26.7%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
11.0%
Steady Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
25%
Cash Flow Needs Attention

Deep Research

Next earnings:Apr 29, 2026
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EPS:-
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Financials
Earnings Calls
Reports
News
Income Statement
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Ratios
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LTM
No Data