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AstraZeneca PLC

AstraZeneca PLC

NASDAQ•AZN
CEO: Mr. Pascal Soriot D.V.M., M.B.A.
Sector: Healthcare
Industry: Drug Manufacturers - General
Listing Date: 1993-05-12
AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company's marketed products include Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Farxiga, Brilinta, Lokelma, Roxadustat, Andexxa, Crestor, Seloken, Onglyza, Bydureon, Fasenra, Breztri, Symbicort, Saphnelo, Tezspire, Pulmicort, Bevespi, and Daliresp for cardiovascular, renal, metabolism, and oncology. Its marketed products also comprise Vaxzevria, Beyfortus, Synagis, FluMist, Soliris, Ultomiris, Strensiq, Koselugo, and Kanuma for covid-19 and rare disease. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Neurimmune AG to develop and commercialize NI006; BenevolentAI for drug discovery for systemic lupus erythematosus; Lunit for developing AI-Powered Digital Pathology Risk Assessment Tools for NSCLC; and Absci Corporation for AI-driven drug discovery against an oncology target. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.
Contact Information
1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0AA, United Kingdom
44-20-3749-5000
www.astrazeneca.com
Market Cap
$276.26B
P/E (TTM)
32.7
23.2
Dividend Yield
1.5%
52W High
$89.43
52W Low
$61.24
52W Range
99%
3.9
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 3.9 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2015-2024

Financial Dashboard

Q3 2025 Data

Revenue

$15.19B+11.99%
4-Quarter Trend

EPS

$0.82+78.26%
4-Quarter Trend

FCF

$4.45B+119.65%
4-Quarter Trend

2024 Annual Earnings Highlights

Key Highlights

Strong Total Revenue Growth Total Revenue reached 54.07B USD, up 18.0%; growth balanced across focus therapy areas and key geographies.
Operating Profit Exceeds 10B Operating Profit increased 22.1% to 10.00B USD, reflecting strong underlying demand and operational efficiency gains.
Oncology Portfolio Drives Sales Oncology sales grew 18% to 20.28B USD, driven by Tagrisso, Imfinzi, and Calquence performance across global markets.
US Market Sales Surge US Product Sales increased 21% to 21.66B USD, reflecting strong growth in Oncology, Ultomiris, and Symbicort demand.

Risk Factors

Pipeline Delivery and Launch Risk Failure or delay in new drug development damages R&D reputation, adversely affecting future business and results of operations.
Pricing and Affordability Pressure Global cost-containment measures, including US IRA, reduce product value sooner than planned, impacting R&D pipeline yield.
Supply Chain and Quality Failure Inability to maintain compliant supply leads to product shortages, lost sales, negative regulatory findings, and reputational damage.
Intellectual Property Erosion Risk Loss of patent protection due to challenges accelerates generic competition, potentially causing material adverse impact on financial results.

Outlook

Robust Late-Stage Pipeline Progress Pipeline features 18 Phase III/Pivotal Phase II assets, focusing on Oncology, CVRM, and Rare Disease indications for future growth.
Strategic Pipeline Acquisitions Completed Completed Gracell (1.04B USD) and Fusion (2.20B USD) acquisitions in 2024, strengthening cell therapy and radioconjugate pipelines.
Emerging Markets Growth Focus Emerging Markets sales grew 15% (23% CER) to 13.54B USD, driven by Oncology and CVRM demand expansion.
Shareholder Return Commitment Declared and paid 4.60B USD in dividends (2.97 USD/share) in 2024, maintaining commitment to shareholder return policy.

Peer Comparison

Revenue (TTM)

GSK plcGSK
$297.24B
+849.3%
Johnson & JohnsonJNJ
$92.15B
+5.1%
Merck & Co., Inc.MRK
$64.24B
+1.7%

Gross Margin (Latest Quarter)

Eli Lilly and CompanyLLY
82.9%
+1.9 pp
Merck & Co., Inc.MRK
81.9%
+6.4 pp
AstraZeneca PLCAZN
81.2%
-0.2 pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
LLY$920.99B49.9102.3%37.0%
JNJ$472.05B18.932.7%3.3%
ABBV$410.63B172.0498.8%51.3%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
+0.7%
Moderate Growth
4Q Net Income CAGR
+19.1%
Profitability Improved
Cash Flow Stability
100%
Strong Cash Flow

Research & Insights

Reports
All Years
  • Form 20-F - FY 2024

    Period End: Dec 31, 2024|Filed: Feb 18, 2025|
    Revenue: $54.07B+18.0%
    |
    EPS: $1.14-40.4%
    Beat
  • Form 20-F - FY 2023

    Period End: Dec 31, 2023|Filed: Feb 20, 2024|
    Revenue: $45.81B+3.3%
    |
    EPS: $1.91+79.7%
    Beat
  • Form 20-F - FY 2022

    Period End: Dec 31, 2022|Filed: Feb 21, 2023|
    Revenue: $44.35B+18.5%
    |
    EPS: $1.06+2550.0%
    Beat
  • Form 20-F - FY 2021

    Period End: Dec 31, 2021|Filed: Feb 22, 2022|
    Revenue: $37.42B+40.6%
    |
    EPS: $0.04-96.7%
    Miss
  • Form 20-F - FY 2020

    Period End: Dec 31, 2020|Filed: Feb 16, 2021|
    Revenue: $26.62B+9.2%
    |
    EPS: $1.22+136.9%
    Miss