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AstraZeneca PLC

NASDAQ•AZN
CEO: Mr. Pascal Soriot D.V.M., M.B.A.
Sector: Healthcare
Industry: Drug Manufacturers - General
Listing Date: 1993-05-12
AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacture, and commercialization of prescription medicines. The company's marketed products include Tagrisso, Imfinzi, Lynparza, Calquence, Enhertu, Orpathys, Truqap, Zoladex, Faslodex, Farxiga, Brilinta, Lokelma, Roxadustat, Andexxa, Crestor, Seloken, Onglyza, Bydureon, Fasenra, Breztri, Symbicort, Saphnelo, Tezspire, Pulmicort, Bevespi, and Daliresp for cardiovascular, renal, metabolism, and oncology. Its marketed products also comprise Vaxzevria, Beyfortus, Synagis, FluMist, Soliris, Ultomiris, Strensiq, Koselugo, and Kanuma for covid-19 and rare disease. The company serves primary care and specialty care physicians through distributors and local representative offices in the United Kingdom, rest of Europe, the Americas, Asia, Africa, and Australasia. It has a collaboration agreement with Neurimmune AG to develop and commercialize NI006; BenevolentAI for drug discovery for systemic lupus erythematosus; Lunit for developing AI-Powered Digital Pathology Risk Assessment Tools for NSCLC; and Absci Corporation for AI-driven drug discovery against an oncology target. The company was formerly known as Zeneca Group PLC and changed its name to AstraZeneca PLC in April 1999. AstraZeneca PLC was incorporated in 1992 and is headquartered in Cambridge, the United Kingdom.
Contact Information
1 Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge, CB2 0AA, United Kingdom
44-20-3749-5000
www.astrazeneca.com
Market Cap
$157.73B
P/E (TTM)
30.2
20.6
Dividend Yield
1.5%
52W High
$212.71
52W Low
$122.48
52W Range
90%
Rank43Top 50.7%
3.8
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 3.8 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$15.50B+0.00%
4-Quarter Trend

EPS

$3.02+0.00%
4-Quarter Trend

FCF

$1.38B+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Total Product Sales Growth Total Product Sales reached $55.57B in 2025, marking a strong 9% increase, driven by all therapy areas.
Oncology Sales Momentum Oncology sales grew 16% to $23.70B, led by Tagrisso and Imfinzi performance across key geographies.
Strong US Market Performance US Product Sales increased 8% to $23.44B, reflecting continued growth in Oncology and Rare Disease segments.
Profit Before Tax Improvement Profit before tax reached $12.40B in 2025, significantly up from $8.69B in 2024, showing operating leverage.

Risk Factors

Pipeline Failure Risk Continued success depends on launching innovative drugs; failure or delay in pipeline delivery damages reputation and future operations.
Regulatory Approval Delays Delays in regulatory approvals adversely affect revenue ability to market products, potentially requiring costly post-approval clinical trials.
Pricing and Affordability Pressures Dynamic economic and political pressures globally increase cost-containment measures, pressuring net price realization across 80 countries.
Cybersecurity Threat Exposure Critical IT systems are vulnerable to sophisticated breaches, risking disclosure of confidential data, regulatory penalties, and reputational harm.

Outlook

Advanced Pipeline Progression Pipeline features numerous Phase III/Pivotal assets, with key data readouts anticipated throughout 2026 and 2027 across Oncology.
AI Technology Investment Significant resources invested in AI development to speed drug discovery, optimize manufacturing, and drive efficiency gains.
Managing Tax Complexity Navigating complex global tax laws, including potential changes from international bodies, requires ongoing management of tax liabilities.
ADR Program Termination Completed delisting from Nasdaq and terminated ADR program effective February 2026, moving to direct NYSE listing.

Peer Comparison

Revenue (TTM)

JNJ stock ticker logoJNJ
$94.19B
+6.0%
LLY stock ticker logoLLY
$65.18B
+44.7%
MRK stock ticker logoMRK
$65.01B
+1.3%

Gross Margin (Latest Quarter)

MRK stock ticker logoMRK
92.7%
+2.2pp
GILD stock ticker logoGILD
86.8%
+0.7pp
JNJ stock ticker logoJNJ
86.4%
+18.0pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
LLY$883.99B40.797.9%37.8%
JNJ$585.70B22.033.8%24.1%
ABBV$369.19B88.0-361.6%51.4%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
4.5%
Moderate Growth
4Q Net Income CAGR
-7.3%
Declining Profitability
Cash Flow Stability
100%
Strong Cash Flow

Deep Research

Next earnings:Apr 27, 2026
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