
Sana Biotechnology, Inc.
NASDAQ•SANA
CEO: Dr. Steven D. Harr M.D.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2021-02-04
Sana Biotechnology, Inc., a biotechnology company, focuses on utilizing engineered cells as medicines. It develops ex vivo and in vivo cell engineering platforms for various therapeutic areas with unmet treatment needs, including oncology, diabetes, central nervous system disorders, B-cell-mediated autoimmune, and others. The company's product candidates include SC291 that is used as allogeneic cell therapies for hematologic malignancies; ARDENT for a potential treatment for non-Hodgkin's lymphoma, and chronic lymphoblastic leukemia; GLEAM, to treat multiple autoimmune disorders that involve production of autoimmune antibodies, including lupus nephritis, extrarenal lupus, antineutrophil cytoplasmic antibody -associated vasculitis, and others. It is developing SC262 to treat patients with relapsed and/or refractory B-cell malignancies; SC255 for multiple myeloma treatment; SC379, a therapy for patients with certain central nervous system disorders healthy allogeneic glial progenitor cells; SC451, a product candidate to treat diabetes, with an initial focus on type 1 diabetes mellitus; and UP421 that reduces long-term exogenous insulin dependence. The company has an option and license agreement with Beam Therapeutics Inc. for use of Beam's proprietary CRISPR Cas12b nuclease editing technology to research, develop, and commercialize engineered cell therapy products; and a license agreement with Harvard College to access certain intellectual property for the development of hypoimmune-modified cells. The company was formerly known as FD Therapeutics, Inc. and changed its name to Sana Biotechnology, Inc. in September 2018. Sana Biotechnology, Inc. was incorporated in 2018 and is headquartered in Seattle, Washington.
Contact Information
Market Cap
$1.10B
P/E (TTM)
-3.9
40.4
Dividend Yield
--
52W High
$7.30
52W Low
$1.26
52W Range
Rank55Top 68.5%
3.0
F-Score
Modified Piotroski Analysis
Based on 7-year fundamentals
Weak • 3 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2018-2024
Financial Dashboard
Q3 2025 Data
Revenue
$0.00+0.00%
4-Quarter Trend
EPS
-$0.16-36.00%
4-Quarter Trend
FCF
-$29.47M-47.29%
4-Quarter Trend
2025 Q3 Earnings Highlights
Key Highlights
R&D Expenses Significantly Reduced Nine-month R&D expenses dropped $73.472M to $97.056M following November 2024 portfolio prioritization efforts.
Net Loss Narrows Substantially Nine-month net loss improved $32.349M to $(185.341)M, driven by lower operating expenses across the board.
Operating Cash Burn Decreased Net cash used in operating activities decreased $64.805M to $(111.187)M for the nine months ended September 30, 2025.
Risk Factors
Major Asset Impairment Recorded $44.611M non-cash impairment loss recognized in nine months due to facility restructuring and business plan adjustments.
Contingent Liability Valuation Risk Long-term contingent consideration liability stands at $115.141M, subject to fluctuations based on market capitalization changes.
Future Financing Requirements Critical Current liquidity supports one year, but substantial additional financing is necessary to fund clinical trials and operations.
Novel Technology Development Risk Platforms rely on unproven technologies; development timelines and regulatory approval success remain highly uncertain.
Outlook
Focus on SC451 and SG293 Prioritizing development of SC451 (T1D) and SG293 (Fusogen Platform) programs; suspending two other CAR T programs.
Key IND Filing Timelines Expect to file IND for SC451 in early 2026 and for SG293 as early as 2027 to advance clinical stages.
Liquidity Covers Next Year Existing cash plus net proceeds from recent Offering and ATM facility expected to fund operations for at least one year.
Peer Comparison
Revenue (TTM)
$111.55M
$109.23M
$26.75M
Gross Margin (Latest Quarter)
IMNM100.0%
95.4%
74.5%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| PRAX | $6.44B | -26.1 | -60.1% | 0.2% |
| NUVB | $3.10B | -14.3 | -55.0% | 1.7% |
| WVE | $2.93B | -24.6 | -72.9% | 76.4% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
N/M
Revenue Volatile
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Research & Insights
Next earnings:Mar 16, 2026
EPS:-$0.12
|Revenue:-
Reports
All Years
Form 10-Q - Q3 2025
Period End: Sep 30, 2025|Filed: Nov 6, 2025|Revenue: $0.00+0.0%|EPS: $-0.16-36.0%N/AForm 10-Q - Q2 2025
Period End: Jun 30, 2025|Filed: Aug 11, 2025|Revenue: $0.00+0.0%|EPS: $-0.39+85.7%N/AForm 10-Q - Q1 2025
Period End: Mar 31, 2025|Filed: May 8, 2025|Revenue: $0.00+0.0%|EPS: $-0.21-57.1%N/AForm 10-K - FY 2024
Period End: Dec 31, 2024|Filed: Mar 17, 2025|Revenue: $0.00+0.0%|EPS: $-1.16+20.5%N/AForm 10-Q - Q3 2024
Period End: Sep 30, 2024|Filed: Nov 8, 2024|Revenue: $0.00+0.0%|EPS: $-0.25-5100.0%N/AForm 10-Q - Q2 2024
Period End: Jun 30, 2024|Filed: Aug 8, 2024|Revenue: $0.00+0.0%|EPS: $-0.21-64.4%N/AForm 10-Q - Q1 2024
Period End: Mar 31, 2024|Filed: May 8, 2024|Revenue: $0.00+0.0%|EPS: $-0.49+14.0%N/AForm 10-K - FY 2023
Period End: Dec 31, 2023|Filed: Feb 29, 2024|Revenue: $0.00+0.0%|EPS: $-1.46-2.1%N/A