
Pacific Biosciences of California, Inc.
NASDAQ•PACB
CEO: Mr. Christian O. Henry M.B.A.
Sector: Healthcare
Industry: Medical - Devices
Listing Date: 2010-10-27
Pacific Biosciences of California, Inc. designs, develops, and manufactures sequencing solution to resolve genetically complex problems. The company provides sequencing systems; consumable products, including single molecule real-time (SMRT) technology; long-red sequencing; and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats, including molecular biology reagents, such as ligase, buffers, and exonucleases. It also offers binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing; and sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. In addition, it provides revio system + sequel systems which conduct, monitor, and analyze single-molecule biochemical reactions in real time; SBB short-read sequencing; onso instrument conducts, monitors, and analyzes SBB biochemical reactions; and SBB consumable, including flow cells, clustering, and sequencing reagent kits. The company serves academic and governmental research institutions; commercial testing and service laboratories; genome centers; public health labs, hospitals and clinical research institutes, and contract research organizations; pharmaceutical companies; and agricultural companies. It markets its products through a sales force and distribution partners in Asia, Australia, Europe, the Middle East, Africa, and Latin America. It has a development and commercialization agreement with Invitae Corporation; and a collaboration with Radboud University Medical to explore genetic causes of rare and genetic diseases. The company was formerly known as Nanofluidics, Inc. and changed its name to Pacific Biosciences of California, Inc. in 2005. Pacific Biosciences of California, Inc. was incorporated in 2000 and is headquartered in Menlo Park, California.
Contact Information
Market Cap
$667.22M
P/E (TTM)
-1.3
32.4
Dividend Yield
--
52W High
$2.73
52W Low
$0.85
52W Range
Rank67Top 97.6%
1.4
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 1.4 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025
Financial Dashboard
Q3 2025 Data
Revenue
$38.44M-3.82%
4-Quarter Trend
EPS
-$0.13-40.91%
4-Quarter Trend
FCF
-$18.62M-58.32%
4-Quarter Trend
2025 Q3 Earnings Highlights
Key Highlights
Gross Profit Significantly Rises Q3 Gross Profit reached $15.9M USD, marking a 59% increase versus Q3 2024, driven by lower cost of revenue and higher consumables sales.
Contingent Liability Settled Contingent consideration liability reduced to $0 USD from $18.7M USD at December 31, 2024, following strategic shift away from short-read development.
Q3 Net Loss Reduced Q3 Net Loss narrowed to $(38.0)M USD, a $22.7M improvement compared to the $(60.7)M loss reported in the same period last year.
Consumables Revenue Growth Continues Nine months Consumables Revenue grew to $60.3M USD, up $8.7M (17%) year-over-year, reflecting expanded Revio instrument installed base adoption.
Risk Factors
YTD Operating Loss Widens Nine months operating loss increased 60% to $(512.7)M USD, primarily due to $388.6M in restructuring-related costs recognized during the period.
Instrument Sales Cycle Elongated Revio instrument sales cycle remains long due to funding uncertainty among academic and research institutions, impacting instrument revenue realization.
IPR&D Impairment Recorded $15.0M IPR&D impairment charge recorded YTD 2025 due to strategic shift away from the high-throughput short-read platform development.
Reliance on Key Suppliers Operations rely on sole-source third-party manufacturers for critical components, risking supply chain interruption or quality issues impacting production.
Outlook
Vega Platform Full Release Strategic objective focuses on full-scale release of Vega benchtop platform to broaden market reach opportunity and drive sequencing volume.
Accelerate Revio Adoption Drive sample volume growth via SPRQ chemistry, enabling sub-$500 HiFi genome sequencing capability and improving DNA input requirements.
Clinical Strategy Progressing Revio increasingly used in LDTs and clinical research settings to consolidate complex genetic testing needs, supporting market leadership goal.
Cash Sufficiency Confirmed Existing cash, cash equivalents, and investments of $298.7M USD are believed sufficient to fund projected operating requirements beyond the next 12 months.
Peer Comparison
Revenue (TTM)
$844.60M
$818.06M
AVNS$699.90M
Gross Margin (Latest Quarter)
KIDS73.9%
72.2%
BVS67.0%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| CTKB | $690.47M | -53.7 | -3.3% | 7.1% |
| PACB | $667.22M | -1.3 | -289.5% | 87.5% |
| LAB | $599.92M | -4.7 | -29.3% | 5.1% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
-0.7%
Flat Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Research & Insights
Next earnings:Aug 3, 2026
EPS:-
|Revenue:-
Reports
All Years
Form 10-Q - Q3 2025
Period End: Sep 30, 2025|Filed: Nov 6, 2025|Revenue: $38.44M-3.8%|EPS: $-0.13-40.9%MeetForm 10-Q - Q2 2025
Period End: Jun 30, 2025|Filed: Aug 7, 2025|Revenue: $39.77M+10.4%|EPS: $-0.14-78.1%BeatForm 10-Q - Q1 2025
Period End: Mar 31, 2025|Filed: May 12, 2025|Revenue: $37.15M-4.3%|EPS: $-1.44+396.6%MissForm 10-K - FY 2024
Period End: Dec 31, 2024|Filed: Mar 17, 2025|Revenue: $154.01M-23.2%|EPS: $-1.13+6.6%MissForm 10-Q - Q3 2024
Period End: Sep 30, 2024|Filed: Nov 12, 2024|Revenue: $39.97M-28.2%|EPS: $-0.22-15.4%MeetForm 10-Q - Q2 2024
Period End: Jun 30, 2024|Filed: Aug 9, 2024|Revenue: $36.01M-24.3%|EPS: $-0.64+128.6%MissForm 10-Q - Q1 2024
Period End: Mar 31, 2024|Filed: May 9, 2024|Revenue: $38.81M-0.2%|EPS: $-0.29-14.7%MissForm 10-K - FY 2023
Period End: Dec 31, 2023|Filed: Feb 28, 2024|Revenue: $200.52M+56.3%|EPS: $-1.21+13.6%Miss