Valneva SE
NASDAQ•VALN
CEO: Mr. Thomas Lingelbach
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2021-05-05
Valneva SE, a specialty vaccine company, develops, manufactures, and commercializes prophylactic vaccines for infectious diseases with unmet needs. It offers IXIARO, an inactivated Vero cell culture-derived Japanese encephalitis vaccine indicated for active immunization against Japanese encephalitis; DUKORAL, an oral vaccine for the prevention of diarrhea caused by Vibrio cholera and/or heat-labile toxin producing enterotoxigenic Escherichia coli bacterium; IXCHIQ, a single-dose, live-attenuated vaccine for the prevention of disease caused by chikungunya virus; and VLA2001, an inactivated whole-virus COVID-19 vaccine. The company also develops VLA15, a vaccine candidate, which is in Phase III clinical trial against Borrelia, the bacterium that causes Lyme disease; VLA1553, a vaccine candidate, which is in Phase III clinical trial against the chikungunya virus; VLA1554, a vaccine candidate targeting human metapneumovirus; and VLA2112, a vaccine candidate to treat patients with epstein-barr virus. It sells its products in the United States, Canada, Germany, Austria, Nordics, the United Kingdom, France, rest of European countries, and internationally. Valneva SE has collaborations with Pfizer, Inc. to co-develop and commercialize its Lyme disease vaccine; and Instituto Butantan for the development, manufacturing, and marketing of single-shot chikungunya vaccine. The company was founded in 1998 and is based in Saint-Herblain, France.
Contact Information
Market Cap
$556.60M
P/E (TTM)
-3.3
22.9
Dividend Yield
--
52W High
$12.25
52W Low
$5.06
52W Range
Rank67Top 97.6%
1.4
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 1.4 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025
Financial Dashboard
Q1 2026 Data
Revenue
$36.17M+0.00%
4-Quarter Trend
EPS
-$0.44+0.00%
4-Quarter Trend
FCF
-$661.38K+0.00%
4-Quarter Trend
2025 Annual Earnings Highlights
Key Highlights
Revenue Increased 3.0% Total revenues reached €174.7M in 2025, a 3.0% increase, driven by IXCHIQ and IXIARO sales growth.
Lyme Vaccine Phase 3 Completed VLA15 Phase 3 VALOR trial completed vaccinations; topline efficacy results anticipated in first half 2026.
New Pharmakon Debt Facility Secured new non-dilutive debt facility up to $500.0M in October 2025, extending maturity to Q4 2030.
Cash Reserves €109.7 Million Cash and cash equivalents stood at €109.7M as of December 31, 2025, funding operations for next 12 months.
Risk Factors
Operating Loss Widened Substantially Operating loss reached €82.1M in 2025, worsening from €13.3M profit in 2024, reflecting high R&D and write-offs.
U.S. IXCHIQ License Withdrawn Voluntarily withdrew U.S. BLA for IXCHIQ in January 2026 following FDA suspension due to serious adverse events reports.
FDA Audit Issues Livingston Site FDA issued Form 483 letter following February 2026 inspection, preventing U.S. IXIARO BLA supplement approval.
Continued Operating Losses Expected Expect significant operating expenses and net losses for several years as pipeline advancement costs exceed short-term revenues.
Outlook
Awaiting VLA15 Phase 3 Results Pfizer aims to submit BLA/MAA for VLA15 in 2026, contingent upon positive efficacy data readout expected in H1 2026.
Focus on Global IXCHIQ Expansion Continue engaging health authorities globally for IXCHIQ; pilot vaccination strategy ongoing in Brazil to generate real-world evidence.
Advance Shigella S4V2 Candidate S4V2 Phase 2 data expected mid-2026, followed by decision on next steps for Shigella vaccine development.
Optimize French Operations Footprint Strategic initiative announced to consolidate French operations in Lyon and close Saint-Herblain site to streamline efficiency.
Peer Comparison
Revenue (TTM)
$285.61M
$196.12M
$191.45M
Gross Margin (Latest Quarter)
9793.1%
100.0%
100.0%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| DAWN | $2.22B | -20.7 | -23.4% | 0.5% |
| TYRA | $1.99B | -15.7 | -42.7% | 1.4% |
| GHRS | $1.64B | -26.4 | -19.8% | 0.2% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
-12.9%
Growth Under Pressure
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Deep Research
Next earnings:Aug 11, 2026
EPS:-$0.19
|Revenue:$44.14M
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement | LTM |
|---|
No Data