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Neurocrine Biosciences, Inc.

NASDAQ•NBIX
CEO: Mr. Kyle W. Gano Ph.D.
Sector: Healthcare
Industry: Drug Manufacturers - Specialty & Generic
Listing Date: 1996-05-23
Neurocrine Biosciences, Inc. discovers, develops, and markets pharmaceuticals for neurological, neuroendocrine, and neuropsychiatric disorders in the United States and internationally. The company's products include INGREZZA for tardive dyskinesia and chorea associated with Huntington's disease; ALKINDI for adrenal insufficiency; Efmody capsules for classic congenital adrenal hyperplasia; Orilissa tablets for endometriosis; and Oriahnn capsules to treat uterine fibroids. Its product candidates in clinical development include valbenazine to treat dyskinetic cerebral palsy in pediatrics and adults; NBI-921352 to treat developmental and epileptic encephalopathy syndrome in pediatrics and adults; NBI-827104 to treat epileptic encephalopathy with continuous spike-and-wave during sleep; NBI-1076986 to treat movement disorders; crinecerfront to treat congenital adrenal hyperplasia in adults and children; EFMODY to treat congenital adrenal hyperplasia and adrenal insufficiency in adults; valbenazine for the adjunctive treatment of schizophrenia; NBI-1065845 for the treatment of inadequate response to treatment in major depressive disorder; luvadaxistat to treat cognitive impairment related to schizophrenia; NBI-1117568 for the treatment of schizophrenia; NBI-1070770 to treat major depressive disorder; NBI-1117570 for the treatment of symptoms of psychosis and cognition in neurological and neuropsychiatric conditions; and NBI-1117569, NBI-1117567, and NBI-1065890 to treat CNS indications. The company also has license and collaboration agreements with Heptares Therapeutics Limited; Takeda Pharmaceutical Company Limited; Idorsia Pharmaceuticals Ltd; Xenon Pharmaceuticals Inc.; Voyager Therapeutics, Inc.; BIAL – Portela & Ca, S.A.; Mitsubishi Tanabe Pharma Corporation; and AbbVie Inc. The company was incorporated in 1992 and is headquartered in San Diego, California.
Contact Information
12780 El Camino Real, San Diego, CA, 92130, United States
858-617-7600
www.neurocrine.com
Market Cap
$13.01B
P/E (TTM)
27.0
37.5
Dividend Yield
--
52W High
$160.18
52W Low
$84.23
52W Range
60%
Rank38Top 36.9%
4.3
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Average • 4.3 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$805.50M+0.00%
4-Quarter Trend

EPS

$1.54+0.00%
4-Quarter Trend

FCF

$390.80M+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Total Revenue Growth Total revenues reached $2.86B USD in 2025, marking a 21.6% increase over 2024 results.
CRENESSITY Launch Success CRENESSITY achieved $301.2M USD in net product sales during its first full year of launch in 2025.
Strong Operating Cash Flow Cash flow from operations totaled $782.7M USD in 2025, up from $595.4M USD in 2024.
R&D Investment Level Total research and development spend hit $1.02B USD in 2025, representing 35.5% of total revenues.

Risk Factors

Commercialization Execution Risk Failure to maintain effective sales efforts for INGREZZA or successfully launch CRENESSITY may reduce revenue.
Pricing Control Headwinds IRA drug pricing measures, including potential MFP for competitors, could increase competitive pressure on INGREZZA.
Supplier Dependency Risk Reliance on limited third-party suppliers for manufacturing could cause delays or materially affect product supply.
Biologics Development Hurdles Transforming R&D strategy to include biologics requires substantial investment and may face development difficulties.

Outlook

Sales Team Expansion Completion Planned expansion of INGREZZA and CRENESSITY sales teams expected completion by end of Q1 2026.
Osavampator Phase 3 Data Phase 3 clinical program for osavampator in MDD expects initial topline data availability in 2027.
Pipeline Cadence Goal Strategy aims to launch approximately one new medicine every two years, driving long-term shareholder value.
New IND Filings Planned Company plans to file IND for NBIP-2118 (obesity therapy) in H1 2026, advancing pipeline balance.

Peer Comparison

Revenue (TTM)

UHS stock ticker logoUHS
$17.36B
+9.7%
VTRS stock ticker logoVTRS
$14.30B
-3.0%
SNN stock ticker logoSNN
$11.61B
+9.9%

Gross Margin (Latest Quarter)

NBIX stock ticker logoNBIX
97.8%
-0.5pp
DOCS stock ticker logoDOCS
89.9%
+0.2pp
SNN stock ticker logoSNN
70.6%
+0.8pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
ILMN$19.61B23.134.9%38.4%
HOLX$16.91B31.311.0%27.5%
VTRS$16.74B-4.8-23.0%39.5%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
12.0%
Steady Growth
4Q Net Income CAGR
169.0%
Profitability Improved
Cash Flow Stability
100%
Strong Cash Flow

Deep Research

Next earnings:May 4, 2026
|
EPS:$1.66
|
Revenue:$771.03M
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement
LTM
No Data