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Alkermes plc

NASDAQ•ALKS
CEO: Mr. Richard F. Pops
Sector: Healthcare
Industry: Biotechnology
Listing Date: 1991-07-16
Alkermes plc, a biopharmaceutical company, researches, develops, and commercializes pharmaceutical products to address unmet medical needs of patients in therapeutic areas in the United States, Ireland, and internationally. It has a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia and bipolar I disorder and a pipeline of clinical and preclinical product candidates in development for neurological disorders. Its marketed products include ARISTADA, an intramuscular injectable suspension for the treatment of schizophrenia; ARISTADA INITIO for the treatment of schizophrenia in adults; VIVITROL for the treatment of alcohol and prevention of opioid dependence; and LYBALVI, an oral atypical antipsychotic drug candidate for the treatment of adults with schizophrenia and bipolar I disorder. It has collaboration agreements primarily with Janssen Pharmaceutica N.V., Janssen Pharmaceutica Inc, and Janssen Pharmaceutica International. The company also offers proprietary technology platforms to third parties to enable them to develop, commercialize, and manufacture products. Alkermes plc was founded in 1987 and is headquartered in Dublin, Ireland.
Contact Information
Connaught House, 1 Burlington Road Dublin 4, Dublin, D04 C5Y6, Ireland
353-1-772-8000
www.alkermes.com
Market Cap
$5.62B
P/E (TTM)
23.0
19
Dividend Yield
--
52W High
$36.48
52W Low
$25.17
52W Range
76%
Rank49Top 66.7%
3.2
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 3.2 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$384.55M+0.00%
4-Quarter Trend

EPS

$0.30+0.00%
4-Quarter Trend

FCF

$170.09M+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Proprietary Product Sales Increase Net product sales reached $1,184.6M in 2025, showing a $101.1M increase driven by LYBALVI unit growth.
Strong Operating Cash Generation Cash provided by operating activities totaled $520.8M in 2025, significantly increasing from $439.1M reported in 2024.
Avadel Acquisition Completed Successfully closed Avadel Acquisition in February 2026, adding narcolepsy product LUMRYZ to proprietary commercial portfolio.
Increased Neuroscience R&D Spend Total R&D expenses rose to $324.0M in 2025, reflecting a $78.7M increase driven by Alixorexton advancement.

Risk Factors

Proprietary Product Revenue Reliance Success heavily depends on manufacturing and commercializing key proprietary products amid intense biopharmaceutical competition.
Reimbursement Level Volatility Product sales revenue growth faces risk from payer reimbursement policies, cost-sharing increases, and potential pricing controls.
Intellectual Property Litigation Risk Uncertainty exists regarding IP validity and enforceability; litigation costs and adverse outcomes could materially affect financial condition.
Regulatory Compliance Burden Failure to comply with extensive legal/regulatory requirements, including REMS for LUMRYZ, risks investigations, penalties, and business losses.

Outlook

Alixorexton Phase 3 Initiation Plan to initiate Phase 3 program for novel orexin 2 receptor agonist Alixorexton in narcolepsy during first quarter of 2026.
Manufacturing Transition Finalized Subcontracting arrangements for VUMERITY manufacture at the Athlone Facility concluded by the end of fiscal year 2025.
Share Repurchase Authorization $200.0M remains authorized for share repurchases under the Repurchase Program, subject to market conditions and board discretion.

Peer Comparison

Revenue (TTM)

PTCT stock ticker logoPTCT
$1.73B
+114.5%
ALKS stock ticker logoALKS
$1.48B
-5.2%
ARWR stock ticker logoARWR
$1.09B
+4081.8%

Gross Margin (Latest Quarter)

KYMR stock ticker logoKYMR
2763.6%
-2680.7pp
ARWR stock ticker logoARWR
97.6%
+50.6pp
PTGX stock ticker logoPTGX
94.9%
+0.0pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
ARWR$8.93B44.236.1%19.5%
PCVX$8.89B-11.0-25.9%7.5%
KRYS$7.82B37.818.7%0.7%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
7.9%
Steady Growth
4Q Net Income CAGR
30.0%
Profitability Improved
Cash Flow Stability
100%
Strong Cash Flow

Deep Research

Next earnings:Apr 29, 2026
|
EPS:-$0.43
|
Revenue:$358.74M
Financials
Earnings Calls
Reports
News
Income Statement
Balance Sheet
Cash Flow Statement
Ratios
% Chg.
Income Statement
LTM
No Data