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CareDx, Inc

NASDAQ•CDNA
CEO: Mr. Abhishek Jain
Sector: Healthcare
Industry: Medical - Diagnostics & Research
Listing Date: 2014-07-17
CareDx, Inc. engages in the discovery, development, and commercialization of diagnostic solutions for transplant patients and caregivers in the United States and internationally. It also provides AlloSure Kidney, a donor-derived cell-free DNA (dd-cfDNA) solution for kidney transplant patients; AlloMap Heart, a gene expression solution for heart transplant patients; AlloSure Heart, a dd-cfDNA solution for heart transplant patients; and AlloSure Lung, a dd-cfDNA solution for lung transplant patients. The company offers Olerup SSP, which is used to type human leukocyte antigen (HLA) alleles based on sequence specific primer technology; QTYPE that enables precision in HLA typing; and Ottr, a transplant patient management software. In addition, it provides AlloSeq Tx, a high-resolution HLA typing solution; AlloSeq cfDNA, a surveillance solution to measure dd-cfDNA in blood; AlloSeq HCT, a solution for chimerism testing for stem cell transplant recipients; Allocell, a surveillance solution that monitors the level of engraftment and persistence of allogeneic cells for patients who have received cell therapy transplants; and XynQAPI cloud-based transplant quality management software, as well as AlloCare, a mobile app that offers a patient-centric resource for transplant recipients. The company offers its products directly to customers, as well as through third-party distributors and sub-distributors. It has a license agreement with Illumina, Inc. for the distribution, development, and commercialization of NGS products and technologies; and Cibiltech SAS to commercialize iBox, a software for the predictive analysis of post-transplantation kidney allograft loss. The company was formerly known as XDx, Inc. and changed its name to CareDx, Inc. in March 2014. The company was incorporated in 1998 and is headquartered in South San Francisco, California.
Contact Information
8000 Marina Boulevard, Brisbane, South San Francisco, CA, 94005, United States
415-287-2300
caredx.com
Market Cap
$825.49M
P/E (TTM)
-38.4
34.1
Dividend Yield
--
52W High
$21.49
52W Low
$10.96
52W Range
48%
Rank58Top 85.6%
2.3
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 2.3 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025

Financial Dashboard

Q4 2025 Data

Revenue

$108.39M+0.00%
4-Quarter Trend

EPS

-$0.08+0.00%
4-Quarter Trend

FCF

$19.73M+0.00%
4-Quarter Trend

2025 Annual Earnings Highlights

Key Highlights

Total Revenue Increased 14% Total revenue reached $379.8M USD, marking a $46.0M increase, driven by strong segment performance across testing services.
Patient Digital Solutions Soars Patient and digital solutions revenue grew 31% to $56.9M USD; Product revenue increased 19% to $48.4M USD.
P&L Swing Driven by Litigation Net loss was $21.4M USD in 2025, reversing $52.5M net income from 2024 due to significant litigation expense changes.
Cash Position Remains Strong Cash, cash equivalents, and marketable securities totaled approximately $201.4M USD as of year-end 2025, with no outstanding debt.

Risk Factors

Expect Continued Net Losses Incurred substantial net losses since inception; expects to incur additional net losses for several future years.
High Medicare Revenue Dependency Medicare comprised 46% of 2025 testing services revenue; adverse reimbursement changes severely impact financial performance.
New Diagnostic Adoption Slow Future sales growth depends on clinician and administrator adoption of new diagnostic solutions, which is historically slow.
Reliance on Sole Source Suppliers Reliance on sole source suppliers for critical reagents risks manufacturing disruption if supply continuity is compromised.

Outlook

Accelerate Profitable Growth Strategy Focus on solutions-selling at transplant centers to increase patient acquisition and adherence protocols for profitable growth.
Define TRANSPLANT+ Market Expansion Initiative to expand market by defining transplant broadly, targeting adjacent areas like pre-transplant assessment and immunology.
Drive Operational Excellence Scaling Strategic investments planned for enterprise applications, automation, and AI tools to scale organization efficiently and expand margins.
Generate Clinical Evidence for Coverage Plan to generate clinical evidence to gain optimal payer coverage and achieve revenue per test (RPT) appreciation.

Peer Comparison

Revenue (TTM)

AMN stock ticker logoAMN
$2.73B
-8.5%
EVH stock ticker logoEVH
$1.88B
-26.6%
EMBC stock ticker logoEMBC
$1.08B
-2.5%

Gross Margin (Latest Quarter)

VIR stock ticker logoVIR
672.1%
-54902.1pp
IOVA stock ticker logoIOVA
215.9%
+65.9pp
URGN stock ticker logoURGN
91.3%
-2.2pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
VIR$1.52B-3.0-49.3%18.6%
IOVA$1.23B-3.9-54.5%5.3%
URGN$1.05B-6.9170.2%64.0%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
8.6%
Steady Growth
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
75%
Volatile Cash Flow

Deep Research

Next earnings:Apr 28, 2026
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LTM
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