
Perspective Therapeutics, Inc.
AMEX•CATX
CEO: Mr. Johan M. Spoor
Sector: Healthcare
Industry: Medical - Devices
Listing Date: 2005-11-10
Perspective Therapeutics, Inc., together with its subsidiaries, develops precision-targeted alpha therapies (TAT) for oncology that treats cancer patients across multiple tumor types comprising metastatic disease. The company discovers, designs, and develop its initial programs candidates consists of VMT-a-NET, that is currently in Phase 1/2a clinical trials for patients with unresectable or metastatic somatostatin receptor type 2 (SSTR2) expressing tumors that have not previously received peptide-targeted radiopharmaceutical therapy, such as Lutathera, a beta-emitting therapy; and VMT01, which is currently in Phase 1/2a clinical trials for second-line or later treatment of patients with progressive melanocortin 1 receptor (MC1R) positive metastatic melanoma. Perspective Therapeutics, Inc. has a clinical trial collaboration agreement with Bristol Myers Squibb to evaluate the safety and tolerability of [212Pb] VMT01 in combination with nivolumab in patients with histologically confirmed melanoma and positive MC1R imaging scans. The company was formerly known as Isoray, Inc. and changed its name to Perspective Therapeutics, Inc. in February 2022. Perspective Therapeutics, Inc. was founded in 1998 and is headquartered in Seattle, Washington.
Contact Information
2401 Elliott Avenue, Suite 320, Seattle, WA, 98121, United States
206-676-0900
Market Cap
$173.17M
P/E (TTM)
-1.6
4.1
Dividend Yield
--
52W High
$5.39
52W Low
$1.60
52W Range
Rank58Top 85.6%
2.3
F-Score
Modified Piotroski Analysis
Based on 10-year fundamentals
Weak • 2.3 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2016-2025
Financial Dashboard
Q3 2025 Data
Revenue
$209.00K+0.00%
4-Quarter Trend
EPS
-$0.35+66.67%
4-Quarter Trend
FCF
-$18.28M-30.60%
4-Quarter Trend
2025 Q3 Earnings Highlights
Key Highlights
Cash Position Declines Net cash used in operating activities totaled $57.8M for nine months ended September 30, 2025, down from $8.3M provided in 2024.
R&D Investment Ramps Up Research and development expenses reached $51.3M YTD, representing a $22.5M increase compared to the prior nine-month period.
VMT-a-NET Trial Progress Safety profile remains well tolerated; 46 patients treated in Cohort 2, with Cohort 3 opening for higher dose evaluation.
Liquidity Runway Extended Cash, equivalents, and investments of $174.1M as of September 30, 2025, expected to fund operations into late 2026.
Risk Factors
Widening Operating Losses Operating loss increased $27.8M to $(73.7)M for nine months ended September 30, 2025, driven by increased R&D spending.
Future Capital Requirements Expect recurring losses; management anticipates needing to raise additional capital through dilutive equity or debt financings.
Clinical Data Uncertainty Risk exists that preliminary or interim clinical trial responses may not ultimately result in confirmed positive treatment outcomes.
Raw Material Cost Pressures Evaluating potential impact of U.S. and international trade policies, including tariffs, on costs for supplies and materials.
Outlook
VMT-a-NET Data Submission Plan to submit updated interim results from ongoing Phase 1/2a trial for presentation at medical conferences within next 12 months.
VMT01 Dose Exploration Exploring lower 1.5 mCi dose level for VMT01 monotherapy and combination cohorts; first patients treated in Q1 2025.
PSV359 Trial Activation PSV359 IND approved Q1 2025; activation activities underway for additional sites after three patients were dosed.
Increased Operating Expenses Budgeted monthly operating expenses increasing for R&D and G&A as strategy advances clinical and preclinical assets.
Peer Comparison
Revenue (TTM)
$6.71B
TMCI$218.88M
RXST$142.09M
Gross Margin (Latest Quarter)
91.5%
RXST79.9%
TMCI79.1%
Key Metrics
Symbol | Market Cap | P/E (TTM) | ROE (TTM) | Debt to Assets |
|---|---|---|---|---|
| NPCE | $564.23M | -23.4 | -136.6% | 66.4% |
| RXST | $403.35M | -11.2 | -12.8% | 3.7% |
| ALT | $374.21M | -4.5 | -54.8% | 7.3% |
Long-Term Trends
Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
N/M
Revenue Volatile
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention
Research & Insights
Next earnings:Mar 25, 2026
EPS:-$0.36
|Revenue:-
Reports
All Years
Form 10-Q - Q3 2025
Period End: Sep 30, 2025|Filed: Nov 10, 2025|Revenue: $209.00K+0.0%|EPS: $-0.35+66.7%MissForm 10-Q - Q2 2025
Period End: Jun 30, 2025|Filed: Aug 13, 2025|Revenue: $290.00K+0.0%|EPS: $-0.30+66.7%BeatForm 10-Q - Q1 2025
Period End: Mar 31, 2025|Filed: May 12, 2025|Revenue: $342.00K+0.0%|EPS: $-0.25+0.0%BeatForm 10-K/A - FY 2024
Period End: Dec 31, 2024|Filed: Mar 28, 2025|Revenue: $0.00-100.0%|EPS: $-1.23-44.7%N/AForm 10-K - FY 2024
Period End: Dec 31, 2024|Filed: Mar 26, 2025|Refer to amended dataForm 10-Q - Q3 2024
Period End: Sep 30, 2024|Filed: Nov 12, 2024|Revenue: $0.00-100.0%|EPS: $-0.21+10.5%N/AForm 10-Q - Q2 2024
Period End: Jun 30, 2024|Filed: Aug 13, 2024|Revenue: $0.00-100.0%|EPS: $-0.18-10.0%N/AForm 10-Q - Q1 2024
Period End: Mar 31, 2024|Filed: May 15, 2024|Revenue: $0.00-100.0%|EPS: $-0.25+3576.5%N/A