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Disc Medicine, Inc.

Disc Medicine, Inc.

NASDAQ•IRON
CEO: Dr. Donald William Nicholson Ph.D.
Sector: Healthcare
Industry: Biotechnology
Listing Date: 2020-08-12
Disc Medicine, Inc., together with its subsidiaries, a clinical-stage biopharmaceutical company, engages in the discovery, development, and commercialization of novel treatments for patients suffering from serious hematologic diseases in the United States. The company has assembled a portfolio of clinical and preclinical product candidates that aim to modify fundamental biological pathways associated with the formation and function of red blood cells, primarily heme biosynthesis and iron homeostasis. Its pipeline includes bitopertin for the treatment of erythropoietic porphyrias, including erythropoietic protoporphyria, X-linked protoporphyria, and diamond-blackfan anemia; DISC-0974 for the treatment of anemia of myelofibrosis, and anemia of chronic kidney disease; and DISC-3405 for the treatment of polycythemia vera, and other hematologic disorders. The company's preclinical programs include DISC-0998, for the treatment of anemia associated with inflammatory diseases. Disc Medicine, Inc. was founded in 2017 and is headquartered in Watertown, Massachusetts.
Contact Information
321 Arsenal Street, Suite 101, Watertown, MA, 02472, United States
617-674-9274
www.discmedicine.com
Market Cap
$2.85B
P/E (TTM)
-15.3
40.1
Dividend Yield
--
52W High
$99.50
52W Low
$30.82
52W Range
65%
Rank59Top 87.6%
2.2
F-Score
Modified Piotroski Analysis
Based on 5-year fundamentals
Weak • 2.2 / 9 points
Scoring Range (0-9)
8-9: Excellent Value
6-7: Strong Fundamentals
4-5: Average Quality
0-3: Weak Performance
Data Period: 2021-2025

Financial Dashboard

Q3 2025 Data

Revenue

$0.00+0.00%
4-Quarter Trend

EPS

-$1.77+98.88%
4-Quarter Trend

FCF

-$47.83M+175.60%
4-Quarter Trend

2025 Q3 Earnings Highlights

Key Highlights

Recent Equity Financing Secured Net cash provided by financing $256.7M for nine months; completed $210.9M offering post-period to bolster liquidity.
Bitopertin NDA Submitted Submitted NDA for accelerated bitopertin approval in EPP/XLP; awarded Commissioner's National Priority Voucher in October.
Research Spending Ramps Up Nine-month R&D expenses reached $124.4M, increasing $52.5M, supporting pipeline advancement efforts across programs.

Risk Factors

Continued Operating Losses Expected Incurred $151.7M net loss for nine months; expects operating losses to continue indefinitely requiring substantial capital.
Material Internal Control Weakness Material weakness identified in ITGCs; management concluded internal controls over financial reporting were ineffective as of 9/30/2025.
Clinical Trials Success Uncertain No product candidates progressed past Phase 3; development success is highly uncertain, risking material failure or delays.

Outlook

Future Capital Requirements High Expects expenses to increase significantly; may need additional equity or debt financing to fund operations into 2029.
Advance Iron Homeostasis Portfolio Planning Phase 2 trial for DISC-0974 in IBD in Q1 2026; initiating Phase 2 for DISC-3405 in PV in H1 2025.
Prepare For Bitopertin Launch Planning US approval and launch for bitopertin in late 2025 or early 2026, supported by CNPV timeline acceleration.

Peer Comparison

Revenue (TTM)

Travere Therapeutics, Inc.TVTX
$435.83M
+114.2%
Arcutis Biotherapeutics, Inc.ARQT
$317.93M
+129.2%
Adaptive Biotechnologies CorporationADPT
$252.75M
+42.6%

Gross Margin (Latest Quarter)

ImmunityBio, Inc.IBRX
99.4%
-0.6pp
Travere Therapeutics, Inc.TVTX
99.0%
+54.4pp
Arcutis Biotherapeutics, Inc.ARQT
91.2%
+3.5pp

Key Metrics

Symbol
Market Cap
P/E (TTM)
ROE (TTM)
Debt to Assets
CDTX$5.61B-32.2-60.1%0.4%
BLTE$5.48B-82.4-44.1%0.0%
BEAM$3.51B-8.3-42.9%11.5%

Long-Term Trends

Last 4 Quarters
Revenue
Net Income
Operating Cash Flow
4Q Revenue CAGR
N/M
Revenue Volatile
4Q Net Income CAGR
N/M
Profitability Shift
Cash Flow Stability
0%
Cash Flow Needs Attention

Research & Insights

Next earnings:Feb 26, 2026
|
EPS:-$1.71
|
Revenue:-
Reports
All Years
  • Form 10-Q - Q3 2025

    Period End: Sep 30, 2025|Filed: Nov 6, 2025|
    Revenue: $0.00+0.0%
    |
    EPS: $-1.77+98.9%
    N/A
  • Form 10-Q - Q2 2025

    Period End: Jun 30, 2025|Filed: Aug 7, 2025|
    Revenue: $0.00+0.0%
    |
    EPS: $-1.58+53.4%
    N/A
  • Form 10-Q - Q1 2025

    Period End: Mar 31, 2025|Filed: May 7, 2025|
    Revenue: $0.00+0.0%
    |
    EPS: $-1.02-6.4%
    N/A
  • Form 10-K - FY 2024

    Period End: Dec 31, 2024|Filed: Feb 27, 2025|
    Revenue: $0.00+0.0%
    |
    EPS: $-3.96-15.8%
    N/A
  • Form 10-Q - Q3 2024

    Period End: Sep 30, 2024|Filed: Nov 12, 2024|
    Revenue: $0.00+0.0%
    |
    EPS: $-0.89+53.4%
    N/A
  • Form 10-Q - Q2 2024

    Period End: Jun 30, 2024|Filed: Aug 8, 2024|
    Revenue: $0.00+0.0%
    |
    EPS: $-1.03+39.2%
    N/A
  • Form 10-Q - Q1 2024

    Period End: Mar 31, 2024|Filed: May 9, 2024|
    Revenue: $0.00+0.0%
    |
    EPS: $-1.09-9.2%
    N/A
  • Form 10-K - FY 2023

    Period End: Dec 31, 2023|Filed: Mar 21, 2024|
    Revenue: $0.00+0.0%
    |
    EPS: $-3.42+92.4%
    N/A